Journal: EBioMedicine

Article Title: Dolutegravir plus lamivudine for maintenance of HIV viral suppression in adults with and without historical resistance to lamivudine: 48-week results of a non-randomized, pilot clinical trial (ART-PRO)

doi: 10.1016/j.ebiom.2020.102779

Figure Lengend Snippet: Demographic and Baseline characteristics for the enrolled participants (n=41).

Article Snippet: Participants were selected from our prior study that evaluated the concordance in detecting persistence of resistance-associated mutations in aviremic persons using proviral DNA population and next-generation sequencing genotyping (“GEN-PRO”) .

Techniques: Biomarker Discovery, Transmission Assay, Clinical Proteomics, DNA Sequencing

Journal: Metabolites

Article Title: What Has Longitudinal ‘Omics’ Studies Taught Us about Irritable Bowel Syndrome? A Systematic Review

doi: 10.3390/metabo13040484

Figure Lengend Snippet: The characteristics and key findings of the studies reviewed (arranged alphabetically by the first author’s last name).

Article Snippet: Ankersen, 2021 [ ] , Denmark , 34 IBS patients (either IBS-D or IBS-M) randomised to receive either web-based low FODMAP diet intervention or probiotic; Rome III criteria for diagnosis , Stool sample , CeGaT GmbH culture-independent, whole-genome, shotgun metagenomic, next-generation sequencing of genomic DNA , Four time points, during the course of 1 year , - web-based low FODMAP diet intervention and probiotic intervention were both efficacious in managing IBS symptoms - in both cases, treatment response could not be predicted or explained by the composition of host gut microbiota.

Techniques: Biomarker Discovery, Microarray, Real-time Polymerase Chain Reaction, Functional Assay, Expressing, Next-Generation Sequencing, Bacteria, Gene Expression, Genome Wide, Probiotics, Isolation, Amplification, Sequencing, Starch, Fluorescence, FACS, Concentration Assay, Control, Clinical Proteomics, RNA Sequencing, Modification